Revealing Selection in Breeding and Genetic Characteristics of Economically Important Traits of New Species of Apostichopus Japonicas Based on Genome Resequencing and GWAS Analysis

Apostichopus japonicas is an economically important species with high nutritional value. However, our knowledge of its genetic diversity and the changes that occurred during domestication or trait selection quite limited. In this study, whole genomes 254 A . samples were resequenced. Analyses population structure revealed A. in north China generally high, there was no difference among six cultured populations, they divided into two subpopulations together AY-1 (new species). The results also showed relatively low, degree linkage alleles had been subjected to more positive selection. Based on Tajima’s D, F ST analysis, ROD selected intervals genes identified, some candidate being related breeding target, namely, number parapodia. Gene Ontology analysis differed their immune function, protein synthesis, decomposition, transport, others. Using GWAS, we identified 39 for four traits , verified those contained non-synonymous SNPs. Through verification, BSL78_00022 BSL78_00023 found be key parapodia Of these genes, encodes a cell differentiation proliferation, so it assumed three substitutions (Ser-Phe, Glu-Asp, Ala-Val) gene are Meanwhile, pleiotropic BSL78_04631, which body weight wall weight, promotes synthesis growth, has substitution (IlE-Val), reason These provide new perspective explaining characteristics analyzing species.